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一種靈活的手套式電化學(xué)生物傳感器
具有高度可拉伸的印刷電極系統(tǒng)
開發(fā)為可穿戴的防御點使用篩選工具
和食品安全應(yīng)用。這是一次性機(jī)械的
堅固的“手套實驗室”集成了可伸縮的可印刷品
基于酶的生物傳感系統(tǒng)和用于滑動的活性表面
在不同的手指上采樣,并與緊湊相結(jié)合
用于電化學(xué)檢測和實時的電子接口
無線數(shù)據(jù)傳輸?shù)街悄苁謾C(jī)設(shè)備。 Stressenduring
墨水用于打印電極系統(tǒng)和
長蛇形連接到無線電子接口。
動態(tài)機(jī)械變形,彎曲和拉伸研究
說明印刷痕跡的彈性和順應(yīng)性
防止這種膠片的極端機(jī)械變形
采樣/傳感操作。食指上的有機(jī)磷水解酶(OPH)生物傳感器系統(tǒng)能夠?qū)崿F(xiàn)
在可疑表面和農(nóng)產(chǎn)品上快速現(xiàn)場檢測有機(jī)磷(OP)神經(jīng)毒劑化合物
跟隨他們在拇指上的滑動收集。新的基于無線手套的生物傳感器系統(tǒng)具有相當(dāng)大的前景
用于國防和食品安全應(yīng)用中OP神經(jīng)毒劑和農(nóng)藥的現(xiàn)場篩查,具有顯著的速度和成本
好處。這種“手套實驗室”演示打開了靈活的可穿戴傳感器領(lǐng)域,面向未來的現(xiàn)場多路復(fù)用
各種領(lǐng)域的化學(xué)檢測。
關(guān)鍵詞:可穿戴傳感器,手套實驗室,拉伸,化學(xué)戰(zhàn)劑,有機(jī)磷水解酶,機(jī)械應(yīng)力,
ABSTRACT: A flexible glove-based electrochemical biosensor
with highly stretchable printed electrode system has been
developed as a wearable point-of-use screening tool for defense
and food security applications. This disposable-mechanically
robust “l(fā)ab-on-a-glove” integrates a stretchable printable
enzyme-based biosensing system and active surface for swipe
sampling on different fingers, and is coupled with a compact
electronic interface for electrochemical detection and real-time
wireless data transmission to a smartphone device. Stressenduring
inks are used to print the electrode system and the
long serpentine connections to the wireless electronic interface.
Dynamic mechanical deformation, bending, and stretching studies
illustrate the resilience and compliance of the printed traces
against extreme mechanical deformations expected for such onglove
sampling/sensing operation. An organophosphorus hydrolase (OPH)-based biosensor system on the index finger enables
rapid on-site detection of organophosphate (OP) nerve-agent compounds on suspicious surfaces and agricultural products
following their swipe collection on the thumb finger. The new wireless glove-based biosensor system offers considerable promise
for field screening of OP nerve-agents and pesticides in defense and food-safety applications, with significant speed and cost
advantages. Such “l(fā)ab-on-a-glove” demonstration opens the area of flexible wearable sensors to future on-the-hand multiplexed
chemical detection in diverse fields.
KEYWORDS: wearable sensor, lab-on-a-glove, stretching, chemical warfare agent, organophosphorus hydrolase, mechanical stress,
food security